Gfpt1 conditional Knockout mouse

Target

Gene symbol :

Gfpt1

NCBI gene ID :

14583

Gene full name :

Glutamine-fructose-6-phosphate transaminase 1

Synonym :

GFA, GFAT1, Gfat

Protein function

Protein name :

GFPT1

Catalyzes rate-limiting step in hexosamine biosynthetic pathway; key for glycosylation.

Expected phenotype

Neuromuscular transmission defects

Human disease relevance

Mutations cause congenital myasthenic syndromes

Model applications

Muscle glycosylation, metabolism

Keywords:

GlcNAc, Myasthenia, Glycosylation

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Gfpt1

conditional Knockout mouse

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