Gja8 conditional Knockout mouse

Target

Gene symbol :

Gja8

NCBI gene ID :

14616

Gene full name :

Gap junction protein, alpha 8

Synonym :

Cx50, Connexin-50, Cx-50

Protein function

Protein name :

GJA8

Lens-specific gap junction channel mediating cell-cell communication.

Expected phenotype

Cataracts, lens fiber degeneration

Human disease relevance

Mutations cause congenital cataracts

Model applications

Eye development, lens communication

Keywords:

Connexin, Cataract, Lens biology

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Gja8

conditional Knockout mouse

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