Grn conditional Knockout mouse

Target

Gene symbol :

Grn

NCBI gene ID :

14824

Gene full name :

Granulin precursor

Synonym :

Granulin

Protein function

Protein name :

Progranulin

Growth factor involved in wound repair, inflammation, and neurodegeneration.

Expected phenotype

Neurodegeneration, immune dysregulation

Human disease relevance

Linked to frontotemporal dementia (FTD)

Model applications

Neuroinflammation, FTD modeling, wound healing

Keywords:

Progranulin, FTD, Inflammation

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Grn

conditional Knockout mouse

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