Gtf2h2 conditional Knockout mouse

Target

Gene symbol :

Gtf2h2

NCBI gene ID :

23894

Gene full name :

General transcription factor IIH subunit 2

Synonym :

GTF-IIH subunit p44

Protein function

Protein name :

GTF2H2

Component of TFIIH complex; vital for transcription initiation and DNA repair

Expected phenotype

Developmental delay, UV-sensitivity

Human disease relevance

Mutations cause trichothiodystrophy, cancer predisposition

Model applications

Transcription initiation and DNA repair models

Keywords:

TFIIH, Transcription, DNA repair

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Gtf2h2

conditional Knockout mouse

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