Hprt conditional Knockout mouse

Target

Gene symbol :

Hprt

NCBI gene ID :

15452

Gene full name :

Hypoxanthine Phosphoribosyltransferase 1

Synonym :

Hprt1

Protein function

Protein name :

HPRT1

Enzyme in purine salvage pathway; converts hypoxanthine to IMP.

Expected phenotype

Neurological dysfunctions, hyperuricemia

Human disease relevance

Mutations cause Lesch-Nyhan syndrome.

Model applications

Purine metabolism and neurological disorder models

Keywords:

Purine metabolism, Neurology, Lesch-Nyhan

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
WoldWide delivery by professional breeders

Hprt

conditional Knockout mouse

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