Hprt1 conditional Knockout mouse

Target

Gene symbol :

Hprt1

NCBI gene ID :

15452

Gene full name :

Hypoxanthine guanine phosphoribosyltransferase

Synonym :

HPRT, HGPRT

Protein function

Protein name :

HPRT enzyme

Enzyme in purine salvage pathway converting hypoxanthine and guanine to nucleotides

Expected phenotype

Hyperuricemia, neurological defects in knockout models

Human disease relevance

Lesch-Nyhan syndrome

Model applications

Metabolism and disease modeling, classic reporter locus

Keywords:

purine metabolism, salvage pathway

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Hprt1

conditional Knockout mouse

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