Target

Gene symbol :  
Hsf2bp
NCBI gene ID :  
74377
Gene full name :  
Heat shock transcription factor 2 binding protein
Synonym :  
MEILB2

Protein function

Protein name :  
HSF2-binding protein
Mediates meiotic recombination; interacts with BRCA2 and recombination factors

Expected phenotype

Knockouts show impaired fertility and defective meiosis

Human disease relevance

Associated with premature ovarian insufficiency

Model applications

Used in meiosis and fertility studies

Keywords:

Meiosis, Fertility, Recombination, BRCA2

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Hsf2bp

conditional Knockout mouse

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