Target

Gene symbol :  
Ide
NCBI gene ID :  
15925
Gene full name :  
Insulin Degrading Enzyme
Synonym :  
-

Protein function

Protein name :  
IDE
Degrades insulin and other peptides; involved in glucose metabolism.

Expected phenotype

Altered insulin clearance, glucose intolerance

Human disease relevance

Associated with type 2 diabetes and Alzheimer's disease.

Model applications

Metabolic and neurodegenerative disease models

Keywords:

Insulin metabolism, Diabetes, Alzheimer's

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Ide

conditional Knockout mouse

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