Il12a conditional Knockout mouse

Target

Gene symbol :

Il12a

NCBI gene ID :

16159

Gene full name :

Interleukin 12a

Synonym :

IL-12p35

Protein function

Protein name :

IL-12p35

Subunit of the cytokine IL-12, involved in the differentiation of naive T cells into Th1 cells.

Expected phenotype

Decreased NK cell responses, altered T cell differentiation, and increased susceptibility to parasitic infections.

Human disease relevance

Implicated in autoimmune diseases and infections.

Model applications

Research on immune responses and cytokine signaling.

Keywords:

Cytokine, Th1 differentiation, Immunity

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Il12a

conditional Knockout mouse

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