Irak2 conditional Knockout mouse

Target

Gene symbol :

Irak2

NCBI gene ID :

108960

Gene full name :

Interleukin-1 receptor-associated kinase 2

Synonym :

IRAK-2

Protein function

Protein name :

Serine/threonine-protein kinase IRAK2

Mediates signaling for IL-1 and TLRs; involved in NF-κB activation

Expected phenotype

Knockouts impair immune responses to infection

Human disease relevance

Implicated in immune regulation and inflammation

Model applications

Studied in innate immunity and cytokine signaling

Keywords:

TLR signaling, NF-κB, Inflammation, Immune response

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Irak2

conditional Knockout mouse

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