Ivd conditional Knockout mouse

Target

Gene symbol :

Ivd

NCBI gene ID :

56357

Gene full name :

Isovaleryl-CoA dehydrogenase

Synonym :

IVD, IVDH

Protein function

Protein name :

IVD

Enzyme in leucine catabolism decoding isovaleric acid

Expected phenotype

Elevated isovaleric acid, metabolic acidosis

Human disease relevance

Mutations cause isovaleric acidemia (organic acidemia)

Model applications

Metabolic disorder, enzyme deficiency models

Keywords:

Leucine catabolism, Organic acidemia

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Ivd

conditional Knockout mouse

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