Jchain conditional Knockout mouse

Target

Gene symbol :

Jchain

NCBI gene ID :

16069

Gene full name :

Joining chain of multimeric IgA and IgM

Synonym :

IgJ

Protein function

Protein name :

J chain

Facilitates polymerization of IgA and IgM for mucosal immunity.

Expected phenotype

Impaired mucosal antibody function

Human disease relevance

Associated with immune deficiencies

Model applications

Mucosal immunity, antibody secretion

Keywords:

IgA, IgM, B-cell function

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Jchain

conditional Knockout mouse

Get in touch about

Let us know how can help

Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe