Target

Gene symbol :  
Jmjd6
NCBI gene ID :  
107817
Gene full name :  
Jumonji domain containing 6
Synonym :  
PSR, PTDSR, Jumonji domain containing 6

Protein function

Protein name :  
Bifunctional arginine demethylase and lysyl-hydroxylase
Regulates histone modification, RNA splicing, and apoptosis

Expected phenotype

Knockouts cause perinatal lethality and developmental defects

Human disease relevance

Implicated in cancer, immune regulation, and tissue remodeling

Model applications

Used in epigenetics, RNA splicing, and immune regulation research

Keywords:

Demethylase, Hydroxylase, RNA splicing, Epigenetics

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Jmjd6

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe