Target

Gene symbol :  
Klhl20
NCBI gene ID :  
226541
Gene full name :  
Kelch-like family member 20
Synonym :  

Protein function

Protein name :  
Kelch-like protein 20
Part of E3 ubiquitin ligase complex; regulates autophagy and hypoxia response

Expected phenotype

Limited data in mouse models

Human disease relevance

Overexpressed in certain cancers (prostate, glioblastoma)

Model applications

Studied in autophagy, ubiquitination, and cancer

Keywords:

Kelch domain, E3 ligase, Hypoxia, Autophagy

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Klhl20

conditional Knockout mouse

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Scientific excellence

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Collaboration with 17 Top Pharmas,
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Robust validation data on catalog models

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Innovative technologies

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Easy access to models

Models with certified health status from professional breeders in US and Europe