Lamb2 conditional Knockout mouse

Target

Gene symbol :

Lamb2

NCBI gene ID :

16779

Gene full name :

Laminin subunit beta 2

Synonym :

Laminin β2

Protein function

Protein name :

LAMB2

Extracellular matrix component essential for glomerular basement membrane integrity.

Expected phenotype

Proteinuria, nephrotic syndrome

Human disease relevance

Mutations cause Pierson syndrome

Model applications

Kidney filtration, ECM modeling

Keywords:

Basement membrane, Glomerulus, Laminin

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Lamb2

conditional Knockout mouse

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