Target

Gene symbol :  
Lamb2
NCBI gene ID :  
16779
Gene full name :  
Laminin subunit beta 2
Synonym :  
Laminin β2

Protein function

Protein name :  
LAMB2
Extracellular matrix component essential for glomerular basement membrane integrity.

Expected phenotype

Proteinuria, nephrotic syndrome

Human disease relevance

Mutations cause Pierson syndrome

Model applications

Kidney filtration, ECM modeling

Keywords:

Basement membrane, Glomerulus, Laminin

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Lamb2

conditional Knockout mouse

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