Ldlr conditional Knockout mouse

Target

Gene symbol :

Ldlr

NCBI gene ID :

16835

Gene full name :

Low density lipoprotein receptor

Synonym :

Low-density lipoprotein receptor, Hlb301

Protein function

Protein name :

LDLR

Mediates endocytosis of cholesterol-rich LDL particles; crucial for cholesterol homeostasis.

Expected phenotype

Hypercholesterolemia, atherosclerosis

Human disease relevance

Mutations cause familial hypercholesterolemia.

Model applications

Research on lipid metabolism and cardiovascular diseases.

Keywords:

Cholesterol metabolism, Lipid transport, Atherosclerosis

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Ldlr

conditional Knockout mouse

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