Target

Gene symbol :  
Lepr
NCBI gene ID :  
16847
Gene full name :  
Leptin receptor
Synonym :  
LEP-R, OB-R, CD295, LEPRD, DB

Protein function

Protein name :  
LEPR
Receptor for leptin; regulates body weight, energy expenditure, and neuroendocrine function.

Expected phenotype

Obesity, infertility, diabetes

Human disease relevance

Mutations lead to severe obesity and metabolic disorders.

Model applications

Studies on obesity, metabolism, and endocrine function.

Keywords:

Energy homeostasis, Obesity, Metabolic regulation

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Lepr

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe