Lifr conditional Knockout mouse

Target

Gene symbol :

Lifr

NCBI gene ID :

16880

Gene full name :

Leukemia inhibitory factor receptor

Synonym :

LIF receptor subunit alpha, CD118

Protein function

Protein name :

LIFR

Receptor for leukemia inhibitory factor; involved in cell differentiation, survival, and proliferation.

Expected phenotype

Perinatal lethality, neural defects

Human disease relevance

Associated with Stüve-Wiedemann syndrome.

Model applications

Research on cytokine signaling and developmental biology.

Keywords:

Cytokine receptor, Neural development, Cell survival

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
WoldWide delivery by professional breeders

Lifr

conditional Knockout mouse

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