Lmnb1 conditional Knockout mouse

Target

Gene symbol :

Lmnb1

NCBI gene ID :

16906

Gene full name :

Lamin B1

Synonym :

Lamin B1

Protein function

Protein name :

Lamin-B1

Structural component of the nuclear lamina; maintains nuclear integrity and regulates gene expression.

Expected phenotype

Demyelination, neurodegeneration

Human disease relevance

Mutations cause autosomal dominant leukodystrophy.

Model applications

Studies on nuclear architecture and neurodegenerative diseases.

Keywords:

Nuclear lamina, Gene regulation, Leukodystrophy

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Lmnb1

conditional Knockout mouse

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