Target

Gene symbol :  
Lnx2
NCBI gene ID :  
140887
Gene full name :  
Ligand of numb-protein X 2
Synonym :  
PDZRN2

Protein function

Protein name :  
E3 ubiquitin-protein ligase LNX2
Acts as a scaffold and E3 ligase; regulates Notch signaling and neurogenesis

Expected phenotype

Limited phenotype characterization; redundancy with LNX1

Human disease relevance

Implicated in neurogenesis and cancer signaling pathways

Model applications

Studied in ubiquitin signaling and neural development

Keywords:

Ubiquitin ligase, Scaffold protein, Notch signaling, Neurogenesis

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Lnx2

conditional Knockout mouse

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