Target

Gene symbol :  
Lpcat1
NCBI gene ID :  
210992
Gene full name :  
Lysophosphatidylcholine acyltransferase 1
Synonym :  
Ayct, Ayct1

Protein function

Protein name :  
LPC acyltransferase 1
Catalyzes conversion of lysophosphatidylcholine to phosphatidylcholine; essential in surfactant production

Expected phenotype

Knockouts show respiratory distress and perinatal lethality

Human disease relevance

Deficiency linked to pulmonary disorders

Model applications

Used in lung biology and lipid metabolism research

Keywords:

Surfactant synthesis, Lipid metabolism, Lung function, LPCAT

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Lpcat1

conditional Knockout mouse

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