Lsm10 conditional Knockout mouse

Target

Gene symbol :

Lsm10

NCBI gene ID :

116748

Gene full name :

LSM10, U7 small nuclear RNA associated

Synonym :

—

Protein function

Protein name :

U7 snRNP core protein LSm10

Component of the U7 snRNP complex involved in histone pre-mRNA 3′ end processing

Expected phenotype

Essential for proper histone mRNA maturation; knockout is embryonically lethal

Human disease relevance

Impaired function may affect chromatin assembly and cell cycle regulation

Model applications

Studied in histone processing and RNA splicing

Keywords:

snRNP, Histone mRNA, RNA processing, Chromatin

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Lsm10

conditional Knockout mouse

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