Mad2l2 conditional Knockout mouse

Target

Gene symbol :

Mad2l2

NCBI gene ID :

71890

Gene full name :

Mitotic arrest deficient-like 2

Synonym :

Mad2B, Rev7

Protein function

Protein name :

Mitotic spindle checkpoint protein MAD2L2

Regulates cell cycle checkpoint, DNA repair, and translesion synthesis

Expected phenotype

Knockout mice exhibit genomic instability and developmental arrest

Human disease relevance

Associated with cancer, DNA repair defects, and immunodeficiency

Model applications

Used in DNA damage response and mitotic checkpoint studies

Keywords:

DNA repair, Cell cycle, Checkpoint, Translesion synthesis

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Mad2l2

conditional Knockout mouse

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