Map2k7 conditional Knockout mouse

Target

Gene symbol :

Map2k7

NCBI gene ID :

26400

Gene full name :

Mitogen-activated protein kinase kinase 7

Synonym :

MKK7, JNKK2

Protein function

Protein name :

MAP2K7 (MKK7)

Activates JNK pathway; involved in stress response, neuronal development, and apoptosis

Expected phenotype

Neuromuscular abnormalities, stress response defects

Human disease relevance

Associated with neurodegenerative disorders and cancer

Model applications

Stress signaling and neural models

Keywords:

JNK pathway, Stress response, Kinase

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Map2k7

conditional Knockout mouse

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