Map3k7 conditional Knockout mouse

Target

Gene symbol :

Map3k7

NCBI gene ID :

26409

Gene full name :

Mitogen-activated protein kinase kinase kinase 7

Synonym :

TAK1, MEKK7, MAPKKK7

Protein function

Protein name :

MAP3K7

Activates JNK and NF‑κB pathways; important for stress and pro-inflammatory signaling

Expected phenotype

Embryonic lethality, immune dysfunction

Human disease relevance

Mutations associated with inflammatory diseases and cancers

Model applications

Inflammation and developmental disease models

Keywords:

Kinase, NF‑κB/JNK, Stress signaling

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Map3k7

conditional Knockout mouse

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