Map4k1 conditional Knockout mouse

Target

Gene symbol :

Map4k1

NCBI gene ID :

26411

Gene full name :

Mitogen-activated protein kinase kinase kinase kinase 1

Synonym :

HPK1

Protein function

Protein name :

MAP4K1

Activates JNK signaling downstream of TCR stimulation.

Expected phenotype

Impaired T-cell activation

Human disease relevance

Involved in immune regulation and cancer

Model applications

T-cell biology, MAPK pathway, cancer

Keywords:

MAPK, JNK, Immune signaling

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Map4k1

conditional Knockout mouse

Get in touch about

Let us know how we can help

Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe