Target

Gene symbol :  
Mapk10
NCBI gene ID :  
26414
Gene full name :  
Mitogen-activated protein kinase 10
Synonym :  
JNK3, SAPKβ

Protein function

Protein name :  
MAPK10
Neuron-specific JNK; regulates apoptosis and neuronal stress responses

Expected phenotype

Neurodegeneration, behavioral alterations

Human disease relevance

Associated with neurodegenerative diseases and mood disorders

Model applications

Neuroscience and neurodegeneration models

Keywords:

JNK pathway, Neuronal, Apoptosis

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Mapk10

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe