Target

Gene symbol :  
Mapt
NCBI gene ID :  
17762
Gene full name :  
Microtubule-associated protein tau
Synonym :  
Tau, Mtap

Protein function

Protein name :  
Tau
Stabilizes microtubules in neurons; involved in axonal transport.

Expected phenotype

Neurodegeneration, cognitive impairment

Human disease relevance

Linked to Alzheimer's disease, frontotemporal dementia

Model applications

Neurodegeneration, Alzheimer’s models

Keywords:

Tauopathy, Microtubules, Neurobiology

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Mapt

conditional Knockout mouse

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Scientific excellence

From model design to experimental results
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Collaborative approach

Collaboration with 17 Top Pharmas,
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Robust validation data on catalog models

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Innovative technologies

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Easy access to models

Models with certified health status from professional breeders in US and Europe