Marveld2 conditional Knockout mouse

Target

Gene symbol :

Marveld2

NCBI gene ID :

218518

Gene full name :

MARVEL domain containing 2

Synonym :

Tric

Protein function

Protein name :

Tricellulin

Component of tricellular tight junctions; maintains epithelial barrier integrity

Expected phenotype

KO mice show impaired epithelial barrier and hearing loss

Human disease relevance

Mutations cause deafness DFNB49

Model applications

Used in epithelial biology and hearing loss studies

Keywords:

Tight junction, Tricellulin, Deafness, Barrier function

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Marveld2

conditional Knockout mouse

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