Mbtd1 conditional Knockout mouse

Target

Gene symbol :

Mbtd1

NCBI gene ID :

103537

Gene full name :

Malignant brain tumor domain containing 1

Synonym :

—

Protein function

Protein name :

MBT domain-containing protein 1

Binds methylated histones; involved in DNA damage repair and transcriptional regulation

Expected phenotype

Knockouts show altered hematopoiesis and DNA repair defects

Human disease relevance

Implicated in cancer and developmental regulation

Model applications

Studied in chromatin biology and gene expression

Keywords:

Epigenetics, Histone binding, DNA repair, Chromatin

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Mbtd1

conditional Knockout mouse

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