Mcu conditional Knockout mouse

Target

Gene symbol :

Mcu

NCBI gene ID :

215999

Gene full name :

Mitochondrial calcium uniporter

Synonym :

Ccdc109a

Protein function

Protein name :

Mitochondrial calcium uniporter protein

Mediates mitochondrial Ca²⁺ uptake; essential for bioenergetics and cell death regulation

Expected phenotype

KO mice viable but show impaired mitochondrial calcium uptake

Human disease relevance

Linked to cardiac and skeletal muscle pathologies

Model applications

Used in mitochondrial physiology and calcium signaling studies

Keywords:

Mitochondria, Calcium transport, Bioenergetics, MCU complex

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Mcu

conditional Knockout mouse

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