Target

Gene symbol :  
Mipol1
NCBI gene ID :  
73490
Gene full name :  
Mirror-image polydactyly 1
Synonym :  
CCDC193

Protein function

Protein name :  
Mirror-image polydactyly 1 protein
Involved in left–right axis determination and ciliogenesis

Expected phenotype

Knockouts show situs inversus and limb abnormalities

Human disease relevance

Mutations cause mirror-image polydactyly syndrome in humans

Model applications

Used in developmental biology and laterality studies

Keywords:

Left-right axis, Cilia, Development, Polydactyly

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Mipol1

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe