Mis18bp1 conditional Knockout mouse

Target

Gene symbol :

Mis18bp1

NCBI gene ID :

217653

Gene full name :

MIS18 binding protein 1

Synonym :

Oip5, KIAA0841

Protein function

Protein name :

MIS18-binding protein 1

Required for recruitment of CENP-A to centromeres during mitosis

Expected phenotype

KO leads to chromosome missegregation and early lethality

Human disease relevance

Implicated in chromosomal instability and cancer

Model applications

Used in centromere assembly and mitosis studies

Keywords:

CENP-A, Centromere, Chromosome segregation, Mitosis

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Mis18bp1

conditional Knockout mouse

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