Target

Gene symbol :  
Mlec
NCBI gene ID :  
109154
Gene full name :  
Malectin
Synonym :  
Lectin

Protein function

Protein name :  
Malectin
ER-resident lectin that binds Glc2-N-glycan intermediates; part of ER quality control

Expected phenotype

Knockouts impair glycoprotein folding and ER homeostasis

Human disease relevance

May be involved in ER stress-related diseases

Model applications

Studied in ER protein folding and glycoprotein processing

Keywords:

ER quality control, Glycoproteins, Lectin, Protein folding

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Mlec

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe