Mrm1 conditional Knockout mouse

Target

Gene symbol :

Mrm1

NCBI gene ID :

217038

Gene full name :

Mitochondrial rRNA methyltransferase 1

Synonym :

Rpml1

Protein function

Protein name :

21S rRNA methyltransferase, mitochondrial

Catalyzes 2′-O-methylation of mitochondrial 21S rRNA; required for mitochondrial translation

Expected phenotype

KO leads to impaired mitochondrial translation

Human disease relevance

Potential role in mitochondrial disorders

Model applications

Used in studies of mitochondrial ribosomes and translation

Keywords:

Mitochondria, rRNA methylation, Translation, Rpml1

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Mrm1

conditional Knockout mouse

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