Mta1 conditional Knockout mouse

Target

Gene symbol :

Mta1

NCBI gene ID :

116870

Gene full name :

Metastasis associated 1

Synonym :

—

Protein function

Protein name :

Metastasis-associated protein MTA1

Chromatin remodeler; core component of the NuRD complex regulating transcription

Expected phenotype

Knockouts show developmental and immune defects; involved in tumor progression

Human disease relevance

Overexpression linked to cancer metastasis and poor prognosis

Model applications

Studied in chromatin remodeling, transcriptional repression, and cancer

Keywords:

NuRD complex, Chromatin remodeling, Transcription, Cancer

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Mta1

conditional Knockout mouse

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