Target

Gene symbol :  
Mtmr4
NCBI gene ID :  
170749
Gene full name :  
Myotubularin-related protein 4
Synonym :  

Protein function

Protein name :  
Myotubularin-related protein 4
Lipid phosphatase involved in endosomal trafficking and autophagy

Expected phenotype

Knockouts show altered vesicle trafficking and developmental abnormalities

Human disease relevance

May play a role in cellular homeostasis and autophagy disorders

Model applications

Studied in phosphoinositide signaling and vesicle dynamics

Keywords:

Phosphatase, Endosomes, Autophagy, Phosphoinositides

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Mtmr4

conditional Knockout mouse

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