Mybpc3 conditional Knockout mouse

Target

Gene symbol :

Mybpc3

NCBI gene ID :

17868

Gene full name :

Myosin binding protein C, cardiac

Synonym :

cMyBP-C

Protein function

Protein name :

MyBP-C

Structural protein in cardiac sarcomere; regulates cardiac muscle contraction.

Expected phenotype

Cardiac hypertrophy, arrhythmias.

Human disease relevance

Mutations cause familial hypertrophic cardiomyopathy.

Model applications

Models for cardiomyopathy and heart disease.

Keywords:

Cardiac muscle, Sarcomere, Hypertrophic cardiomyopathy

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Mybpc3

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe