Target

Gene symbol :  
Ncoa3
NCBI gene ID :  
17979
Gene full name :  
Nuclear receptor coactivator 3
Synonym :  
AIB1, SRC-3, RAC3, TRAM-1, pCIP, KAT13B

Protein function

Protein name :  
NCOA3
Coactivator for nuclear receptors; enhances transcriptional activation.

Expected phenotype

Altered gene expression; developmental defects.

Human disease relevance

Associated with breast cancer and endometrial hyperplasia.

Model applications

Studies on hormone-dependent cancers and gene regulation.

Keywords:

Transcription coactivator, Hormone signaling, Cancer

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • WoldWide delivery by professional breeders

Ncoa3

conditional Knockout mouse

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