Ndufs1 conditional Knockout mouse

Target

Gene symbol :

Ndufs1

NCBI gene ID :

227197

Gene full name :

NADH:ubiquinone oxidoreductase core subunit S1

Synonym :

—

Protein function

Protein name :

Complex I subunit S1

Core subunit of mitochondrial complex I; involved in oxidative phosphorylation

Expected phenotype

Disruption leads to impaired mitochondrial function

Human disease relevance

Linked to mitochondrial diseases, Leigh syndrome

Model applications

Used in studies of mitochondrial dysfunction

Keywords:

Mitochondria, Complex I, Oxidative phosphorylation, Leigh syndrome

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Ndufs1

conditional Knockout mouse

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