Target

Gene symbol :  
Nebl
NCBI gene ID :  
74103
Gene full name :  
Nebulette
Synonym :  
LASP2

Protein function

Protein name :  
Nebulette
Actin-binding protein involved in myofibril assembly in cardiac and skeletal muscle

Expected phenotype

Knockout mice show cardiac defects and sarcomere disorganization

Human disease relevance

Linked to cardiomyopathy and muscle disorders

Model applications

Used in heart development and sarcomeric structure studies

Keywords:

Cardiac muscle, Sarcomere, Actin-binding, Cardiomyopathy

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Nebl

conditional Knockout mouse

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