Nebl conditional Knockout mouse

Target

Gene symbol :

Nebl

NCBI gene ID :

74103

Gene full name :

Nebulette

Synonym :

LASP2

Protein function

Protein name :

Nebulette

Actin-binding protein involved in myofibril assembly in cardiac and skeletal muscle

Expected phenotype

Knockout mice show cardiac defects and sarcomere disorganization

Human disease relevance

Linked to cardiomyopathy and muscle disorders

Model applications

Used in heart development and sarcomeric structure studies

Keywords:

Cardiac muscle, Sarcomere, Actin-binding, Cardiomyopathy

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Nebl

conditional Knockout mouse

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