Nemo conditional Knockout mouse

Target

Gene symbol :

Nemo

NCBI gene ID :

16151

Gene full name :

Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma

Synonym :

Ikbkg, Ikk-gamma

Protein function

Protein name :

NEMO (IKKγ)

Regulatory subunit of IKK complex activating NF-κB signaling.

Expected phenotype

Impaired immune signaling, embryonic lethality

Human disease relevance

Causes incontinentia pigmenti, immunodeficiency

Model applications

NF-κB signaling, inflammation, genetic disease models

Keywords:

NF-κB, Inflammation, Immunodeficiency

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Nemo

conditional Knockout mouse

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