Target

Gene symbol :  
Nodal
NCBI gene ID :  
18119
Gene full name :  
Nodal growth differentiation factor
Synonym :  
-

Protein function

Protein name :  
Nodal
Secreted ligand of the TGF-beta superfamily; regulates embryonic development.

Expected phenotype

Defects in left-right asymmetry; embryonic lethality.

Human disease relevance

Associated with heterotaxy and congenital heart defects.

Model applications

Studies on embryogenesis and developmental biology.

Keywords:

TGF-beta signaling, Embryonic development, Left-right asymmetry

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Nodal

conditional Knockout mouse

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