Nodal conditional Knockout mouse

Target

Gene symbol :

Nodal

NCBI gene ID :

18119

Gene full name :

Nodal growth differentiation factor

Synonym :

-

Protein function

Protein name :

Nodal

Secreted ligand of the TGF-beta superfamily; regulates embryonic development.

Expected phenotype

Defects in left-right asymmetry; embryonic lethality.

Human disease relevance

Associated with heterotaxy and congenital heart defects.

Model applications

Studies on embryogenesis and developmental biology.

Keywords:

TGF-beta signaling, Embryonic development, Left-right asymmetry

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Nodal

conditional Knockout mouse

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