Notum conditional Knockout mouse

Target

Gene symbol :

Notum

NCBI gene ID :

77583

Gene full name :

Notum palmitoleoyl-protein carboxylesterase

Synonym :

Lipid-modifying enzyme

Protein function

Protein name :

NOTUM

Antagonizes Wnt signaling by depalmitoleoylating Wnt proteins.

Expected phenotype

Developmental abnormalities

Human disease relevance

Implicated in cancer and developmental disorders

Model applications

Wnt modulation, regenerative biology

Keywords:

Wnt inhibitor, Lipid signaling

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Notum

conditional Knockout mouse

Get in touch about

Let us know how can help

Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe