Nploc4 conditional Knockout mouse

Target

Gene symbol :

Nploc4

NCBI gene ID :

217365

Gene full name :

Nuclear protein localization protein 4 homolog

Synonym :

Nip45, Npl4

Protein function

Protein name :

NPL4 homolog

Cofactor for p97/VCP involved in ERAD and ubiquitin-proteasome degradation

Expected phenotype

KO leads to embryonic lethality

Human disease relevance

Associated with neurodegenerative diseases via ERAD pathway

Model applications

Used in protein degradation and ER stress studies

Keywords:

ERAD, VCP cofactor, Protein degradation, Ubiquitin

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Nploc4

conditional Knockout mouse

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