Nras conditional Knockout mouse

Target

Gene symbol :

Nras

NCBI gene ID :

18176

Gene full name :

Neuroblastoma RAS viral oncogene homolog

Synonym :

N-ras, c-N-Ras

Protein function

Protein name :

NRAS

GTPase involved in cell proliferation and differentiation via MAPK/ERK pathway.

Expected phenotype

Abnormal cranial morphology, altered behavior.

Human disease relevance

Mutations linked to various cancers and developmental disorders.

Model applications

Cancer research, developmental biology.

Keywords:

Oncogene, Signal transduction, MAPK pathway

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
WoldWide delivery by professional breeders

Nras

conditional Knockout mouse

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