Nsd3 conditional Knockout mouse

Target

Gene symbol :

Nsd3

NCBI gene ID :

234135

Gene full name :

Nuclear receptor binding SET domain protein 3

Synonym :

Whsc1l1, Wolf-Hirschhorn syndrome candidate 1-like 1

Protein function

Protein name :

Histone-lysine N-methyltransferase NSD3

Methylates H3K36; regulates transcription and chromatin state

Expected phenotype

KO not fully characterized; overexpression promotes tumorigenesis

Human disease relevance

Implicated in breast and lung cancers

Model applications

Used in cancer epigenetics and chromatin remodeling studies

Keywords:

H3K36 methylation, Epigenetics, Chromatin, NSD family

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Nsd3

conditional Knockout mouse

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