Target

Gene symbol :  
Ntrk1
NCBI gene ID :  
18211
Gene full name :  
Neurotrophic tyrosine kinase, receptor, type 1
Synonym :  
TrkA, Trk, Tkr

Protein function

Protein name :  
TrkA
High-affinity receptor for nerve growth factor; critical for neuronal survival and differentiation.

Expected phenotype

Sensory neuron defects, impaired pain perception.

Human disease relevance

Mutations cause congenital insensitivity to pain with anhidrosis.

Model applications

Neurological disorder models, pain research.

Keywords:

Neurotrophin receptor, Neuronal development, Pain signaling

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Ntrk1

conditional Knockout mouse

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