Target

Gene symbol :  
Oasl2
NCBI gene ID :  
23962
Gene full name :  
2'-5'-oligoadenylate synthase-like 2
Synonym :  
2'-5'-oligoadenylate synthetase-like 2

Protein function

Protein name :  
OASL2
Antiviral protein induced by interferons; binds viral RNA and activates RNase L pathway

Expected phenotype

Reduced antiviral response

Human disease relevance

Involvement in immune psychiatric disorders and viral susceptibility

Model applications

Innate immunity and antiviral response models

Keywords:

Antiviral, Interferon-stimulated, Innate immunity

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Oasl2

conditional Knockout mouse

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