Orc5 conditional Knockout mouse

Target

Gene symbol :

Orc5

NCBI gene ID :

26429

Gene full name :

Origin recognition complex subunit 5

Synonym :

Lox1

Protein function

Protein name :

ORC5

Part of origin recognition complex, essential for DNA replication initiation

Expected phenotype

Embryonic lethality, S‑phase defects

Human disease relevance

Implicated in Meier-Gorlin syndrome

Model applications

DNA replication and developmental models

Keywords:

DNA replication, ORC, Cell cycle

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Orc5

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe